Publications
Electrocardiography (ECG), improved by artificial intelligence (AI), has become a potential technique for the precise diagnosis and treatment of cardiovascular disorders. The conventional ECG is a frequently used, inexpensive, and easily accessible test that offers important information about the physiological and anatomical state of the heart. However, the ECG can be interpreted differently by humans depending on the interpreter’s level of training and experience, which could make diagnosis more difficult.
Advancements in Serum Biomarkers for Early Diagnosis and Prognostic Assessment of Aortic Dissection
Aortic dissection (AD) is a potentially fatal cardiovascular issue that needs to be diagnosed and treated very away. While early detection is essential for bettering patient outcomes, there are substantial obstacles with the diagnostic techniques used today. Promising pathways for improving AD prognosis evaluation and early detection are presented by recent developments in serum biomarkers. The most recent research on serum biomarkers for AD is reviewed here, with an emphasis on the prognostic and diagnostic utility of these indicators.
Comparison of long-term clinical outcomes of bioabsorbable polymer versus durable polymer drug-eluting stents: a systematic review and meta-analysis
One million individuals in the USA die from acute myocardial infarction (MI), which currently affects 3 million people globally. The available data about the early and late outcomes of both biodegradable polymer drug-eluting stents (BP-DES) and durable polymer drug-eluting stents exhibit inconsistency. We performed a meta-analysis comparing the safety and efficacy of BP-DES with DP-DES.
- Neoadjuvant therapy has an established role in the treatment of patients with colorectal cancer. It is used to downstage tumors and facilitate surgical resection
- Total neoadjuvant therapy (TNT) is a novel strategy in the management of locally advanced rectal cancer. It involves the use of (chemo)radiotherapy and combined chemotherapy prior to surgery. TNT has been shown to reduce distant metastases, increase disease-free survival, and improve overall survival rates
- The choice of neoadjuvant treatment regimen for colorectal cancer depends on various factors, including the extent/resectability of the primary tumor, the presence of metastatic disease, and the patient’s performance status
- Short-course radiotherapy and long-course chemoradiotherapy are commonly used neoadjuvant treatment regimens for rectal cancer. Short-course radiotherapy improves local disease control, while total neoadjuvant therapy offers advantages over short-course radiotherapy and long-course chemoradiotherapy
- The optimal indications for different neoadjuvant treatment regimens, with respect to surgical complexity, oncological risk, and long-term functional outcomes, are still being determined
Exocrine pancreatic insufficiency in systemic diseases: Unraveling the complex roleplay: A comprehensive review
- Exocrine pancreatic insufficiency (EPI) is a condition characterized by the inadequate production or secretion of pancreatic enzymes, leading to impaired digestion and malabsorption of nutrients. It is commonly associated with diseases of the exocrine pancreas, such as chronic pancreatitis and cystic fibrosis
- Systemic diseases can also contribute to the development of EPI. These include conditions like diabetes mellitus, celiac disease, inflammatory bowel disease, pancreatic tumors, and HIV/AIDS.
- Early and accurate diagnosis of EPI in the setting of systemic diseases is crucial for anticipating the disease’s course and determining appropriate therapeutic interventions
- Screening for EPI as part of the diagnostic work-up for chronic pancreatitis is recommended, and nutritional assessment is an essential component of the standard work-up
- Pancreatic enzyme replacement therapy (PERT) is the mainstay of treatment for EPI. It involves the supplementation of pancreatic enzymes to aid in the digestion and absorption of nutrients. PERT has been shown to improve symptoms, nutritional status, and quality of life in patients with EPI
Advancements in treatment of diuretic resistance in congestive heart failure
- Diuretics play a significant role in the management of congestive heart failure by relieving congestive symptoms and reducing fluid overload
- Diuretic resistance, defined as an inadequate response to diuretic therapy despite an adequate regimen, is a major clinical challenge in the treatment of heart failure
- The appropriate use of diuretics can be challenging due to complications such as electrolyte abnormalities, worsening renal function, and diuretic resistance
- Understanding renal physiology and diuretic pharmacokinetics is essential for skillful use of diuretics in the management of heart failure
- Advancements in the treatment of diuretic resistance in congestive heart failure include the implementation of patient-tailored variability and chronotherapy-guided algorithms to improve diuretic response and long-term beneficial effects